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Daily vinegar ingestion improves depression scores and alters the metabolome in healthy adults: a randomized controlled trial

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BMI body mass index, FBS fasting blood sugar, IRI immunoreactive insulin, HBA1c, hemoglobin A1c, HDL cholesterol high-density lipoprotein cholesterol, LDL cholesterol low-density lipoprotein cholesterol, NEFA non-esterified fatty acid, AST aspartate aminotransferase, ALT alanine aminotransferase, GGT -glutamyl transpeptidase, CAP controlled attenuation parameter, LSM liver stiffness measurement Honda et al

Historically, anti-obesity drugs have shown a lot of negative side effects and only moderate efficacy

Ongoing work continues to investigate its mechanisms, delivery optimisation, and potential applications across sleep science, neuroendocrinology, and stress-related research.